The Sixers begin their road trip tonight in Los Angeles as they square off against Chris Paul and the Clippers (see game notes).
Here is a look at the other notable games tonight in the NBA:
Heat at Cavaliers, 7 p.m.
The Miami Heat look to extend their winning streak to 24 games as they visit LeBron James' old stomping grounds in Cleveland.
The Heat are coming off a 105-103 victory over the Celtics thanks to a game-winning jumper by James in the final seconds.
James returns to Cleveland without much hype thanks to the Heat's winning streak. Since joining the Heat, James has averaged 26.4 points on 51.2 percent shooting, with 6.9 assists and 6.2 rebounds against his former team.
The teams last met on Feb. 24 with the Heat narrowly coming away with a 109-105 victory. Dion Waiters and Kyrie Irving combined for 43 points in the near upset.
Thunder at Grizzlies, 8 p.m.
The Memphis Grizzlies go for their ninth straight home victory Wednesday night as they host the Oklahoma City Thunder.
The Thunder, who sit 1.5 games behind the West-leading Spurs, are coming off a 114-104 loss to the Nuggets on Tuesday. They allowed a season-worst 72 points in the paint to Denver, which leads the NBA by a wide margin in that category.
The Grizzlies will have the task of trying to hand the Thunder a second straight defeat, which has only happened twice this season.
The Grizzlies are coming off a 92-77 victory over the Wolves on Monday, which snapped a two-game losing streak.
The teams have split their meetings this season. Kevin Durant totaled 61 points in those two games.
Warriors at Spurs, 8:30 p.m.
The San Antonio Spurs host Golden State as they look for their 29th straight home victory over the Warriors.
San Antonio is coming off a 119-113 victory over the Irving-less Cavaliers. The Spurs allowed Cleveland to shoot 50.6 percent.
The Spurs have gone 5-2 and maintained the top seed in the West since Tony Parker went down with an ankle injury.
The Warriors have won four of their past give games, including back-to-back road wins by 20 points or more.
The two teams last met on Feb. 22 with the Warriors ending a 16-game losing streak against the Spurs. Jarret Jack scored a season-high 30 points in the 107-101 victory.