The Eagles (5-6) have lost six of their last eight games and travel to Cincinnati to face a Bengals team that dropped to 3-7-1 last week.
Judging by the records, this is a game the Eagles should win easily, but of course it's not that easy. And these two teams aren't that far apart (see story).
The Eagles are absolutely desperate. They would likely need to win their last five games to make the playoffs.
It'll have to start with a win in Cinci this weekend. Here are five matchups to watch.
Wendell Smallwood vs. Bengals' run D
With Ryan Mathews (knee) out again this week, expect to see plenty of rookie Smallwood on Sunday afternoon (see story). He carried the ball just nine times against the Packers, but the Eagles barely ran the ball. On Friday, Doug Pederson said Smallwood wasn't the reason why.
There should be some decent opportunity for Smallwood this weekend against a Bengals defense that has given up 120.5 yards per game on the ground, the fifth worst average in the NFL. They've given up 100-plus yards on the ground if four of the last five weeks.
Allen Barbre vs. Carlos Dunlap
Dunlap leads the Bengals with 6½ sacks and he'll get to face off against Barbre, who's a veteran but is now out of position. With rookie Halapoulivaati Vaitai still out with his knee injury, Barbre is the new right tackle.
Another matchup will be Geno Atkins vs. the Eagles' guards. Atkins lines up on both sides of the line, but he'll likely see plenty of Stefen Wisniewski instead of Brandon Brooks.
Tyler Eifert vs. Malcolm Jenkins/Nigel Bradham
With the injury to A.J. Green, whom Eifert said was the Bengals' best player, Eifert has become Cincinnati's No. 1 target.
He was targeted 11 times and had five catches for 68 yards and a touchdown last week against the Ravens.
He'll see a mix of Jenkins and Bradham on him this Sunday.
Cedric Ogbuehi vs. Brandon Graham
The Bengals have one really good offensive tackle on the left side of the line (Andrew Witworth) and Ogbuehi on the other. So far this season, Ogbuehi, according to ProFootballFocus, has given up eight sacks, three quarterback hits and 29 quarterback hurries. Only three offensive tackles have given up more sacks than Ogbuehi this year.
With Witworth likely shutting down Barwin and with Fletcher Cox likely getting double-teamed inside, Graham vs. Ogbuehi might be the Eagles' best opportunity to create pressure.
Jeremy Hill vs. Eagles run defense
The Eagles, at times this season, have had trouble with running backs who run hard. And they've at times had trouble with missing tackles.
That could be a problem against Hill. This could be a grind-it-out type of game for both teams, which means Hill could play a huge role. Of his 644 rushing yards this year, 404 have come after contact. To put that into perspective, Ezekiel Elliott leads the league in rushing yards after contact, but 62.7 percent of Hill's yards have come after contact, compared to 57 percent of Elliott's.