The Sixers (22-35) finish off a back-to-back set out of the All-Star break when they the New York Knicks (23-35) at Madison Square Garden (7:30 p.m./CSN, CSNPhilly.com and the NBC Sports app).
Let's take a closer look at the matchup.
1. Starting out strong
So much for having nine days off and players in new roles negatively impacting the team.
The Sixers stormed into the home stretch of the season with a 120-112 win over the Washington Wizards. Seven different players scored in double figures for the Sixers, as they knocked off the Eastern Conference's No. 3 seed.
Perhaps no player had a bigger impact on the game than Richaun Holmes. The backup big man notched the first double-double of his career with 12 points and 10 rebounds. He also added a career-best five blocks.
"I try to approach every game this season the same way, whether everybody was playing or people were hurt," Holmes said. "Prepare like I'm going to play 30 minutes a game. I think having that mindset helped me to stay ready at all times and be aggressive when I had a chance."
2. Young guns
Injuries will prevent another juicy clash between Joel Embiid and Kristaps Porzingis, but there will still be two other young players to keep an eye Saturday night.
Dario Saric and Willy Hernangomez have been two of the most impressive rookies this season, especially since the calendar flipped to February.
Saric has averaged 16.4 points, 7.3 boards and 2.2 assists this month. He's coming off a 20-point, 11-rebound performance against the Wizards for his third straight double-double.
Hernangomez has put up 11.0 points, 9.5 rebounds and 2.3 assists a night in February. The center, who was actually drafted 35th overall in 2015 by the Sixers before being traded, recorded 11 points and 10 rebounds in the Knicks' 119-104 loss to the Cleveland Cavaliers on Thursday.
Saturday's clash could go a long way toward determining Rookie of the Month honors for the East.
3. A Rose is but a Rose
Derrick Rose will never be considered among the league's top assist men. That's simply not his style of play.
When the oft-injured Rose has his game flowing, it starts with scoring, particularly against the Sixers.
In 18 career matchups with the Sixers, Rose has averaged 20.7 points. He's also put up 6.6 assists and 3.9 rebounds in those contests.
Rose scored 25 points on 11 of 16 shooting in the Knicks' first meeting with the Sixers this season back on Jan. 12.
That typically would have been enough to say he won the point guard battle that night, but T.J. McConnell's buzzer-beating jumper stole the show in the Sixers' 98-97 win.
Embiid (knee), Tiago Splitter (calf), Ben Simmons (foot) Jerryd Bayless (wrist) are out for the Sixers.
Joakim Noah (hamstring) is a game-time decision. Porzingis (ankle) is out for the Knicks.
5. This and that
• The Sixers' win over the Knicks in their last meeting snapped a five-game skid in the series.
• The Sixers had 28 assists in their win over the Wizards. They are eighth in the NBA with 23.6 assists a night.
• The Knicks are fourth in the NBA in rebounding with 46.0 boards per game.