BUFFALO, N.Y. -- Nigel Hayes' driving layup with 11 seconds gave Wisconsin a 65-62 win over top-ranked and top-seeded Villanova at KeyBank Center, ending the Wildcats' bid to repeat as national champions.
Villanova led by seven at 57-50 with five minutes left, but Wisconsin outscored the Wildcats, 15-5, the rest of the way, limiting Villanova to just one basket during that stretch.
After Hayes put the Badgers ahead, Josh Hart drove the lane with a chance to tie the score, but he was tied up in the paint and lost the ball with four seconds left.
Villanova fouled Wisconsin's Vitto Brown, who hit the first of two foul shots, and Villanova wasn't able to control the rebound until it was too late to put together a potential game-tying three.
Hart finished his brilliant Villanova career with 19 points, freshman Donte DiVincenzo added 15 points and five rebounds and sophomore Jalen Brunson added 11 points, all in the second half.
But they just didn't get enough help, and Villanova's season-long depth issues were glaring against a Wisconsin team that won 26 games this year, was ranked as high as seventh during the season and goes 10 players deep.
Kris Jenkins, the sharp-shooting hero of last year's NCAA Championship Game, continued to struggle, going 2 for 9 from the field and 0 for 2 from range. He was 0 for 8 from three in Villanova's two tournament games and 2 of 19 in the last four games.
Jenkins, Darryl Reynolds and Mikal Bridges, three Villanova starters, combined for just eight points.
What it means
Villanova became the 24th team in the last 25 years to fail to repeat as national champions. Since 1993, only Florida in 2006 and 2007 has won back-to-back national titles.
Villanova also lost for the fourth time in eight years as a No. 1 or No. 2 seed to an opponent seeded No. 7 or lower.
They also lost as a No. 2 seed in 2010 to No. 10 St. Mary's, they lost as a No. 2 seed in 2014 to No. 7 seed UConn -- the eventual national champion -- and they lost as a No. 1 seed in 2015 to No. 8 seed North Carolina State.
Since 2010, No. 1 or 2 seeds are 113-24 vs. teams seeded No. 7 or lower, with Villanova responsible for four of those 24 losses.
Wisconsin improved to 27-9 and advanced to the Sweet 16 for the fourth straight year, fifth time in the last six years and 10th time in the last 18 years.
Stat of the day
These two NCAA games mark the first time Jenkins has failed to hit at least one three-pointer in consecutive games since December 2015 when he was 0 for 4 vs. Delaware and 0 for 2 vs. Penn.
Bronson Koenig hit two deep right-corner threes a minute apart to get Wisconsin back in the game after they trailed by seven with 5:06 to go.
By the numbers
Villanova was just 5 for 16 from three and 1 for 5 in the second half. … For Wisconsin, Koenig, playing much of the game with four fouls, finished with 17 points. Hayes added 19 points and eight rebounds while Ethan Happ added 12 points and eight boards. … Villanova shot 54 percent in the second half but missed three foul shots in the final three minutes.
Wisconsin advanced to the Sweet 16 and will play East Region semifinals at Madison Square Garden in New York on Friday against the winner of a game later Saturday between Florida and Virginia.
This is Wisconsin's 10th trip to the Sweet 16 -- all in the last 17 years. It's the Badgers' fourth straight Sweet 16 and sixth in the last seven years.